Roy Aaron, MD

Adult Reconstruction
Professor of Orthopaedic Surgery

Appointment Information:

Patient Appointments, Surgical Scheduling & Administration
Call: 401-274-9660

Roy Aaron, M.D.

Adult Reconstruction
Professor of Orthopaedic Surgery

Specialties:

Roy Kenneth Aaron, M.D., a specialist in arthritis and metabolic bone disease, is an attending orthopedic surgeon at Miriam Hospital. He is Director of clinical research for the department, and Director of the Orthopaedic Cell Biology Laboratory. He is also Director of the Brown / VA Center for Restorative and Regenerative Medicine.

Dr. Aaron performs arthroscopic and other procedures for joint preservation in arthritis. Dr. Aaron spends a substantial amount of time in the laboratory and is doing research into osteoarthritis and cartilage transplantation using stem cells for joint resurfacing. He is interested in the use of biological alternatives to joint replacements for joint diseases.

Offices:

Dudley Street
2 Dudley St.
Providence, RI
02905

Butler Drive
100 Butler Dr.
Providence, RI
02906

Recent Appointments and Committees

2009- Present
Editorial Board, Orthopaedic Research and Reviews

2007- Present
Reviewer, Osteoarthritis and Cartilage

2003-Present
Scientific Team, Brown - NIH Osteoarthritis Initiative

2000- Present
Reviewer, Journal of Orthopaedic Research

2010
Presenter, “Electrical Stimulation of Bone Repair, Clinical Experiences”, Electric and Electromagnetic Stimulation of Bone and Cartilage Repair; Medical Applications of Electromagnetic Fields: Research and Therapy, Erice, Italy.

2010
Chair, Surgical Interventions and Rehabilitation Study Section, Peer Reviewed Orthopaedic Research Program, Congressionally Directed Medical Research Program, Department of Defense

2010
Discussor, “Prosthetics and Orthotics”, VA/DoD State of the Art Conference, Rehabilitation Research and Development Service, Department of Veterans Affairs

2010
Faculty, Orthopaedic Research Society/ Orthopaedic Research and Education Foundation/ American Academy of Orthopaedic Surgeons, Grant Writing Course

2010
Presenter, “VA/DoD Collaborations”, Center Director’s Conference; Rehabilitation Research and Development Service, Department of Veterans Affairs

2010
NIH CSR Special Emphasis Panel, Musculoskeletal, Oral and Skin Sciences IRG

2010
Moderator, “Imaging”, Musculoskeletal Biology and Bioengineering Gordon Research Conference

2009
NIH CSR Special Emphasis Panel, Musculoskeletal, Oral and Skin Sciences IRG

2009
Moderator, “Visualizing Skeletal Pathology”, 3rd New York Symposium on Skeletal Biology and Medicine

2009
Speaker, “Development Perspective on Regeneration”, State of the Science Workshop: Regenerative Rehabilitation, Walter Reed Army Medical Center

2009
NE Representative, Arthritis Foundation Osteoarthritis Alliance Leadership Group

2007-2009
Board of Directors, Orthopaedic Research Society

My Assistant

Administrative Assistant and Clinical Research Manager
Anne Voisinet
401-274-9660
AVoisinet@lifespan.org

Publications

  • Chen, Y., R. Pareta, B. Bilgen, A. Myles, H. Fenniri, D. McK. Ciombor, R.K. Aaron, T. Webster. Self-assembled rosette nanotube/hydrogel composites for cartilage tissue engineering. Tissue Eng Part C Methods. In Press.
  • Puckett, S., P.P. Lee, D. McK. Ciombor, R.K. Aaron, T. Webster. Nanotextured titanium surfaces for enhancing skin growth on transcutaneous osseointegrated devices. Acta Biomaterialia. 6: 2352-62; 2010.
  • Gerin-Lajoie, M., D. McK. Ciombor, W. Warren, R.K. Aaron.  Using ambulatory virtual environments for the assessment of functional gait impairment: A proof-of-concept study. Gait and Posture. 31: 533-536; 2010.
  • Dyke, J.P., R.K. Aaron.  Non-invasive methods of measuring bone blood perfusion.  Ann. NY Acad. Sci.1192:95-102; 2010.
  • Bilgen B, Y. Ren, M. Pei, R.K. Aaron, D. McK. Ciombor. CD14-Negative isolation enhances chondrogenesis in synovial fibroblasts.  Tissue Eng.  15: 3261-3270; 2009.
  • Lee, J.H., J. Dyke, D. Ballon, D. McK. Ciombor, M. Rosenwasser, R.K. Aaron. Subchondral fluid dynamics in a model of osteoarthritis: Use of dynamic contrast-enhanced magnetic resonance imaging. Osteoarthritis and Cartilage.  17: 1350-1355; 2009.
  • Lee, J.H., J. Dyke, D. Ballon, D. McK. Ciombor, G. Tung, R.K. Aaron. Assessment of bone perfusion with contrast-enhanced magnetic resonance imaging. Ortho Clin N Am. 40: 249-257; 2009.
  • Covey, D. C. Born, R.K. Aaron, D. McK. Ciombor, et. al. Orthopaedic war injuries:  Recent developments in treatments and research. AAOS Instructional Course Lectures. 58: 117-129; 2009.
  • Ciombor, D. McK., R.K. Aaron. Electric, electromagnetic, and acoustic treatment for avascular necrosis of the femoral head. Techniques in Orthopaedics. 23: 11-17; 2008.
  • Jaklenec A, A. Hinckfuss, B. Bilgen, D. McK. Ciombor, R.K. Aaron, E. Mathiowitz. Sequential release of bioactive IGF-I and TGF-?1 from PLGA microsphere-based scaffolds. Biomaterials.10:1518-25; 2008.
  • Covey, D. R.K. Aaron, C. Born, J. Calhoun, T. Einhorn, H. Frisch, L. Levin, M. Mazurek, E. Schwartz, J. Wenke, E. Powell. Orthopaedic war injuries from combat casualty care to definitive treatment: a current review of the basic science, clinical advances and research opportunities. AAOS Instructional Course Lectures. 57: 65; 2008.
  • Bilgen B, E. Orsini, R.K. Aaron, D. McK. Ciombor. FBS suppresses TGF-?1-induced chondrogenesis in synoviocyte pellet cultures while dexamethasone and dynamic stimuli are beneficial. J. Tissue Eng. Regen. M., 1: 436 – 442; 2007.
  • Aaron, R.K., J. Dyke, D. McK. Ciombor, D. Ballon, J. Lee, E. Jung, G. Tung. Perfusion abnormalities in subchondral bone association with marrow edema, osteoarthritis and avascular necrosis. Ann. NY Acad. Sci. 1117: 124-137; 2007.
  • Aaron, R.K., D. McK. Ciombor, M. Lysaght, E. Mathiowitz, M. Ehrlich Regenerative medicine for limb trauma. Medicine and Health/Rhode Island. 90: 6; 2007.
  • Aaron, R.K. and J. Morgan. Biohybrid limbs: New materials and new properties Medicine and Health/Rhode Island. 90: 4; 2007.
  • Aaron, R.K. and R. Gray. Osteonecrosis: Etiology, Natural History, Pathophysiology and Diagnosis. In: The Adult Hip, 2nd edition. Eds: J. Callaghan, A. Rosenberg, and H. Rubash. Lippincott Williams & Wilkins, Philadelphia, PA. v. 1 pg 463-476; 2007.  
  • Aaron, R.K. and D. McK. Ciombor. Orthopaedic complications of solid organ transplantation. Surg. Clin. N Am. 86: 1237-1255; 2006.
  • Aaron, R.K., H. Herr, D. McK. Ciombor, L. Hochberg, J. Donoghue, C. Briant, J. Morgan, M. Ehrlich. Horizons in prosthetic development for restoration of limb function. J. Am. Acad. Orthop. Surg. 14: S198-204: 2006.
  • Paek, H.J., A.B. Campaner, J.L. Kem, L. Golden, R.K. Aaron, D. McK. Ciombor, J. Morgan, M. Lysaght. Microencapsulated cells genetically modified to overexpress human transforming growth factor-beta1: viability and functionality in allogeneic and xenogeneic implant models. Tissue Eng. 12: 1733-9; 2006.
  • Ciombor, D. McK., A Jaklenec, A. Liu, C. Thanos, N. Rahman, P. Weston, R. Aaron, E. Mathiowitz. Encapsulation of BSA using a W/O/O emulsion solvent removal method. J. Microencap. 23: 183-194; 2006.
  • Aaron, R.K., D. McK. Ciombor, S. Wang. Clinical biophysics: The promotion of skeletal repair by physical forces. Ann. N.Y. Acad. Sci. 1068: 513-531; 2006.
  • Aaron, R.K., A. Skolnick, S. Reinert, D. McK. Ciombor. Arthroscopic debridement for osteoarthritis of the knee. J. Bone Joint Surg. 88A: 936-943; 2006.
  • Aaron, R.K., E. Bluman, M.G. Ehrlich, P.G. Trafton.  The Pelvis, Hip and Thigh. In: Netter Textbook of Orthopaedics.  Ed:  W. Greene. p. 363-394, Elsevier Saunders, Philadelphia, PA. 2006.
  • Ciombor, D. McK. and R.K. Aaron. The role of electrical stimulation in bone repair.  Foot and Ankle Clinics. 10: 579- 593; 2005.
  • Paek, H.J., A.B. Campaner, J.L. Kim, R.K. Aaron, D. Ciombor, J. Morgan, M. Lysaght. In-vitro characterization of TGF-?1 release from genetically modified fibroblasts in calcium alginate microcapsules. ASAIO. 51: 379-384, 2005.
  • Aaron, R.K. and M. Bolander (eds.). Physical Regulation of Skeletal Repair. American Academy of Orthopaedic Surgeons, Chicago, IL. 2005.
  • Aaron, R.K., and D. McK. Ciombor. Pain in osteoarthritis. Medicine and Health/RI. 87: 205-209; 2004.
  • Aaron, R.K., B. Boyan, D. McK. Ciombor, Z. Schwartz, B. Simon. Stimulation of growth factor synthesis by electric and electromagnetic fields. Clin Orthop Relat. Res. 419: 30-37; 2004.
  • Aaron, R.K., D. McK. Ciombor, B. Simon. Treatment of nonunions with electric and electromagnetic fields. Clin Orthop. Relat. Res. 419: 21-29; 2004.
  • Shalvoy, R., G. Ferguson, R.K. Aaron. Hip and Knee Pain. In: Primary Care for Women. Eds: P. Leppert and J. Peipert. p. 652-658, Lippincott-Raven, Philadelphia, PA. 2003.
  • Ciombor, D. McK., R.K. Aaron, S. Wang, and B. Simon.  Modification of osteoarthritis in the guinea pig – A morphological study.  Osteoarthritis and Cartilage. 11: 455-462; 2003.
  • Lieberman, J., D. Berry, M. Mont, R.K. Aaron, et al. Osteonecrosis of the hip: Management in the 21st century. AAOS Instructional Course Lectures. 52:337; 2003.
  • Lieberman, J., D. Berry, M. Mont, R.K. Aaron, et al.  Osteonecrosis of the hip: Management in the 21st century. J. Bone Joint Surg. 84: 834-853; 2002.
  • Aaron, R.K., S. Wang, and D. McK. Ciombor.    Upregulation of basal TGF-b levels coincident with chondrogenesis. Implications for skeletal repair and tissue engineering. J. Orthop. Res.  20:  233-240; 2002.
  • Ciombor, D. McK., G. Lester, R.K. Aaron, P. Neame, and B.  Caterson.  Low frequency EMF regulates chondrocyte differentiation and expression of matrix proteins J. Orthop. Res. 20: 40-49; 2002.
  • Aaron, R.K. and D. McK. Ciombor. Coagulopathies in osteonecrosis. Curr. Opin. Ortho. 12: 378-383; 2001.
  • Aaron, R.K.  Concepts of the pathogenesis of osteonecrosis. Techniques in Orthopaedics 16: 101-104; 2001.
  • Aaron, R.K.  Technique of core decompression.  Techniques in Orthopaedics 16: 98-100; 2001.
  • Ciombor, D. McK. and R.K. Aaron.  Biologically augmented core decompression for the treatment of osteonecrosis of the femoral head. Techniques in Orthopaedics 16: 32-38; 2001.
  • Aaron, R.K., B. Stulberg and D. Lennox.  Clinical and radiographic outcomes in untreated symptomatic osteonecrosis of the femoral head.  Techniques in Orthopaedics 16: 1-5; 2001.
  • Collaborative Osteonecrosis Group.  Multifocal osteonecrosis - A multicenter study.  Clin. Orthop. Relat. Res.  369: 312-326; 1999.
  • Aaron, R.K. and D. McK. Ciombor.  Preservation of the hip in osteonecrosis of the femoral head.  In:  Modulazione Biofisica Della Osteogenesi Mediante Campi Elettromagnetici Pulsati. Vol. II; Eds. G.C. Traina, F. Pipino, L. Massari, L. Molfetta, and R. Cadossi. p. 69-74.  Walberti Editore, Ravenna, Italy1999.
  • Ciombor, D. McK. and R.K. Aaron.  EMF stimulates cartilage differentiation in endochondral ossification coincident with an increase in TGF-b expression. In:  Electricity and Magnetism in Biology and Medicine.  Ed; F. Bersani p. 139-144.  Kluwer Academic/Plenum Publishers, New York, NY, 1999.
  • Aaron, R.K., D. McK. Ciombor, H. Keeping, et al.  Power frequency fields promote cell differentiation coincident with an increase in TGF-b expression.  Bioelectromagnetics.20: 453-458, 1999.
  • Aaron, R.K. and D. McK. Ciombor.  Electrical stimulation, demineralized bone matrix, and bone morphogenic protein. Semin. Arthroplasty.  9:221-30, 1998.
  • Carson, J.L., M.L. Terrin, F.B. Barton, R.K. Aaron, A.G. Greenberg, et al.  A pilot randomized trial comparing symptomatic vs. hemoglobin-level-driven red blood cell transfusions following hip fracture.  Transfusion. 38:522-29, 1998.
  • Scully, S., R.K. Aaron and J. Urbaniak.  Survival analysis of hips treated with core decompression or vascularized fibular grafting because of avascular necrosis.  J. Bone Joint Surg. Am.  80:1270, 1998.
  • Aaron, R.K., D. McK. Ciombor and C. Polk.  Therapeutic potential of electric fields in skeletal morphogenesis.  In: Skeletal Growth and Development:  Clinical Issues and Basic Science Advances.  Eds.  J.A. Buckwalter, M.G. Ehrlich, L.J. Sandell, and S.B. Trippel. p. 589-610, AAOS, Chicago, IL. 1998.
  • Aaron, R.K. Musculoskeletal disease (Editorial).  Medicine and Health/Rhode Island. 81:154, 1998.
  • Aaron, R.K.  Importance of the early diagnosis of hip pain: New approaches to hip preservation in osteonecrosis.  Medicine and Health/Rhode Island 81:157, 1998.
  • Polk, C., R.K. Aaron, and D. McK. Ciombor. Therapeutic applications of low frequency electric and magnetic fields in the US. In: Treatment with Electromagnetic Fields. Ed: J.P. Stossel. Schattauer, Stuttgart, Germany. 1997.
  • Aaron, R.K., D. McK. Ciombor, and C.F. Lord.  Core decompression augmented with human decalcified bone matrix graft for osteonecrosis of the femoral head.  In:  The Etiology, Diagnosis and Management of Osteonecrosis of the Human Skeleton. Ed. J. Urbaniak. p. 301, AAOS, Chicago, IL. 1997.
  • Aaron, R.K., D. Lennox and B. Stulberg.  The natural history of osteonecrosis of the femoral head and risk factors for progression.  In: The Etiology, Diagnosis and Management of Osteonecrosis of the Human Skeleton. Ed. J. Urbaniak. p. 261, AAOS, Chicago, IL. 1997.
  • Aaron, R.K.  Osteonecrosis:  Etiology, pathophysiology and diagnosis.  In:    The Adult Hip. Eds:  J. Callaghan, A. Rosenberg, and H. Rubash. p. 451, Raven Press, New York, NY. 1997.
  • Aaron, R.K., and D. McK. Ciombor. The role of electrical stimulation in the treatment of avascular necrosis of the femoral head. Curr. Orthopaed. London, UK. 11:187, 1997.
  • Aaron, R.K. and D. McK. Ciombor.  Acceleration of experimental endochondral ossification by biophysical stimulation of the progenitor cell pool.  J. Ortho. Res. 14: 582-589, 1996.
  • Aaron, R.K. Treatment of osteonecrosis of the femoral head with electrical stimulation In: Impiego Dei Campi Elettromagnetici Pulsati (CEMP) in Orthopedia E Traumatologia.  Eds. G.C. Traina, L. Romanini, L. Massari, C. Villani, and R. Cadossi.  P.69, Walberti Ediore, Ravenna, Italy.  1995.
  • Aaron, R.K. Treatment of osteonecrosis of the femoral head with electrical stimulation.  AAOS Instructional Course Lectures  43:495, 1994.
  • Aaron, R.K. Advances in the surgical treatment of arthritis. R.I. Med. J. 77:16,1994.
  • Aaron, R.K. and D. McK. Ciombor.  Therapeutic effects of electromagnetic fields in the stimulation of connective tissue repair.  J. Cell. Biochem. 52:42-46, 1993.
  • Ciombor, D. McK. and R.K. Aaron.  Influence of electromagnetic fields on endochondral bone formation.  J. Cell. Biochem.  52:37-41, 1993.
  • Gershuni, D., R.K. Aaron, C.T. Brighton, F. Magee, and C.F. Smith. Symposium-Recent Advances in Electrical Stimulation.  Contemp. Ortho. 26:609, 1993.
  • Aaron, R.K. and D. McK. Ciombor.  Electrical stimulation of bone induction and bone grafting.  In: Bone Grafts and Bone Substitutes. Ed.: M. Habal and A.H. Reddi.  p. 192, W.B. Saunders Inc, Philadelphia, PA. 1992.
  • Aaron, R.K. and M.E. Steinberg.  Electrical stimulation of osteonecrosis of the femoral head.  Semin. Arthroplasty. 2:214, 1991.
  • Aaron, R. K., D. Lennox, G. Bunce, D. McK. Ciombor, and T. Ebert.  Durability of outcome in osteonecrosis of the femoral head treated with pulsing electromagnetic fields or core decompression.  In: Electromagnetics in Medicine and Biology. Ed: C.T. Brighton and S.R. Pollack. p.309, San Francisco Press, San Francisco, CA.1991.
  • Savin, H. B., Zimmermann, R.K. Aaron, P. Libbey, J. Alper, and E.V. Lally. Seronegative symmetric polyarthritis in Sezary syndrome. J. Rheumatol. 18:464, 1991.
  • Aaron, R.K. Basic science of fractures and fracture healing. Curr. Opin. Ortho.  1:294, 1990.
  • Aaron, R.K., D. Lennox, G.E. Bunce and T. Ebert.  The conservative treatment of osteonecrosis of the femoral head - A comparison of pulsed electromagnetic fields and core decompression. Seventeenth Open Meeting of the Hip Society.  Clin. Orthop. Relat. Res. 249:209, 1989.
  • Froehlich, J., G.S. Dorfman, J. Cronan, P.J. Urbanek, J.H. Herndon, and R.K. Aaron. Compression ultrasound for detection of deep venous thrombosis in patients with hip fractures: A prospective study.  J. Bone Joint Surg. Am.  71A:249, 1989.
  • Aaron, R.K., D. McK. Ciombor and G. Jolly. Stimulation of experimental endochondral ossification by low-energy pulsing electromagnetic fields.  J. Bone Miner. Res. 4:227-233, 1989.
  • Aaron, R.K., G. Jolly, D. McK. Ciombor, and H-J. Barrach.  A histochemical method for the demonstration of calcifying cartilage.  Calcified Tissue Int. 43:244, 1988.
  • Limbird, R.S. and R.K. Aaron.  Laterally comminuted fracture dislocations of the ankle.  J. Bone Joint Surg. Am.  69A:881, 1987.
  • Aaron, R.K. Patients at risk for femoral osteonecrosis. Diagnosis 9:51, 1987.
  • Aaron, R.K., C.B. Sledge, and S. Shortkroff.  Experimental arthritis induced by polysaccharide macromolecules.  Arthritis Rheum. 30:679, 1987.
  • Aaron, R.K. and R. Scott.  Supracondylar fractures after total knee replacement.  Clin Orthop Relat Res. 219:30, 1987.
  • Aaron, R.K. and D. McK. Ciombor.  Treatment of osteonecrosis of the femoral head with pulsed external magnetic fields. Ann. N.Y. Acad. Sci. 435:367, 1985.
  • Aaron, R.K., D. McK. Ciombor, R. Glasser and S. Bruder.  Quantitative histomorphometric analysis of decalcified bone matrix-induced enchondral ossification.  Ann. N.Y. Acad. Sci.  435:237, 1985.
  • Aaron, R.K. and D. McK. Ciombor.  Venous thromboembolism in orthopaedic surgery.  Surg.Clin. N Am. 63:529, 1983.
  • Aaron, R.K. Total joint arthroplasty. Surg. Clin. N Am. 63:697, 1983.
  • Brook, I. and R.K. Aaron.  Hospital-based aspergillus flavus infection in a surgical wound:  A case report.  Orthopaedics 3:1215, 1980.
  • Aaron, R.K., L. Ellman, A. Carvalho and W.H. Harris.  Relationship of intravascular coagulation and fibrinolysis to venous thrombosis following total hip replacement.  Clin Orthop Relat Res. 135:148, 1978.
  • Aaron, R.K.  Reduction of Hageman factor, prekallikrein, and kininogen in surgical stress.  In:  The Chemistry and Biology of the Kallikrein-Kinin System in Health and Disease.  Eds.:  J.J. Pisano and K.F. Austen.  P. 545.  National Institutes of Health, DHEW 76-791, 1976.
  • Aaron, R.K., R. Beazley and G. Riggle.  Hematologic integrity after intraoperative autotransfusion - a comparison with bank blood.  Arch. Surg.  108:831, 1974.
  • Aaron, R.K., S. Srinivasan and P.N. Sawyer.  Synthetics and Implants. In:  Medical Engineering. Ed: C. D. Ray.  Year Book Medical Publishers, Chicago, Illinois. 1973.
  • Roberts, A.J., R.K. Aaron, D. Conkle, J. Brown, E. Stinson and C. McIntosh.  Lasix and albumin therapy in the post-operative cardiac patient.  Circulation 48 (Suppl):207, 1973.
  • Bennett, S., G. Geelhoed, R.K. Aaron, T. Solis and R. Hoye.  Pulmonary injury resulting from perfusion with stored bank blood in the baboon and the dog. J. Surg. Res. 13:295, 1972.
  • Aaron, R.K., S. Srinivasan, D. Burrowes, and P.N. Sawyer.  Effects of chemical compounds upon current-induced thrombosis in rat mesenteric vessels.  Thromb. et Diath. Haemorr. 23:621, 1970.
  • Aaron, R.K., T. Lucas, S. Srinivasan and P.N. Sawyer.  Alterations in vascular surface charge and propensity to thrombosis produced by blood vessel injury. Bull. N.Y. Acad. Med. 45:969, 1969.
  • Srinivasan, S., R.K. Aaron, P. Chopra, T. Lucas and P.N. Sawyer.  Effects of thrombotic and anti-thrombotic drugs on surface charge characteristics of canine blood vessels in vivo and in vitroSurgery. 64:827, 1968.

 

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University Orthopedics in Providence, Rhode Island, is a regional referral center for patients with back and neck pain, joint pain, sports medicine problems, shoulder pain, hand problems, hip and knee pain, and foot and ankle injury. University Orthopedics utilizes fellowship-trained, sub-specialized physicians to treat a variety of orthopedic problems.

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